Lymphoplasmacytic Lymphoma with Paraprotein IgG

Waldenstrom's macrogloblinemia/ lymphoplasmacytic lymphoma.

Waldenström’s macroglobulinemia (WM) is a distinct clinicopathological entity resulting from the accumulation, predominantly in the bone marrow, of clonally related lymphocytes, lymphoplasmacytic cells and plasma cells which secrete a monoclonal IgM protein (Figure 1). This condition is considered to correspond to the lymphoplasmacytic lymphoma (LPL) as defined by the Revised European American ...

Response to ibrutinib in a patient with IgG lymphoplasmacytic lymphoma carrying the MYD88 L265P gene mutation.

Response to ibrutinib in a patient with IgG lymphoplasmacytic lymphoma carrying the MYD88 L265P gene mutation Jorge J. Castillo, Irene M. Ghobrial & Steven P. Treon To cite this article: Jorge J. Castillo, Irene M. Ghobrial & Steven P. Treon (2016) Response to ibrutinib in a patient with IgG lymphoplasmacytic lymphoma carrying the MYD88 L265P gene mutation, Leukemia & Lymphoma, 57:11, 2699-2701...

A patient with an IgG paraprotein and complexes of lactate dehydrogenase and IgG in the serum.

PRDM1 expression levels in marginal zone lymphoma and lymphoplasmacytic lymphoma

PRDM1 (BLIMP1) is a transcription repressor protein shown to be involved in B-cell differentiation into plasma cells. Marginal zone lymphomas (MZL) and lymphoplasmacytic lymphomas (LPL) are B cell lymphomas that both show some degree of plasmacytic differentiation and thus can sometimes constitute a difficult differential diagnosis. In this study, we investigated if MZL and LPL have abnormaliti...

Lymphoplasmacytic lymphoma presenting as retinal hemorrhage.